Bilateral abducens nerve palsy due to septic thrombophlebitis.

PurposeTo report a case of septic thrombophlebitis producing bilateral abducens nerve palsy.ObservationA 65 year-old woman with recent sinus surgery experienced the onset of horizontal diplopia during treatment for bacteremia. Computer tomography of head and a neck ultrasonography showed right internal jugular vein occlusion. Ophthalmology examination was consistent with bilateral abducens nerve palsy. She was treated with systemic antibiotics and antiplatelet therapy with resolution of the internal jugular vein occlusion. The diplopia improved over a six-months.Conclusion and importanceOur patient had Lemierre syndrome with an unusual presentation. The patient was treated for septic thrombophlebitis with a resolution of her ocular symptoms

A decision support system for fostering smart energy efficient districts

The role of ICT is becoming prominent in tackling some of the urban societal challenges such as energy wastage and increasing carbon emissions. In this context, the concept of DAREED aims to deliver an integrated decision support system (DSS) to drive energy efficiency and low carbon activities at both a building and district level. The main aim of this paper is to present the technical concept of the Best Practices recommendation component of the DAREED system. This component seeks to compare and identify existing best practices to recommend practical actions to various stakeholders (e.g. building managers, citizens) in order to improve energy performance considering the global needs of a building. This paper also discusses the context of the three field trial sites (based in UK, Spain and Italy) in which the DAREED platform along with the best practices tool is to be tested and validated.This work evolved in the context of the project DAREED (Decision support Advisor for innovative business models and useR engagement for smart Energy Efficient Districts), www.dareed.eu, a project cofunded by the EC within FP7, Grant agreement no: 609082

Principali patogeni e difesa

Olive as other woody perennial crops can be affected by several systemic pathogens, including bacteria, fungi and several vector-borne viruses. The most important olive diseases, caused by different pathogens, are described in this text. Pathogen biology, diagnostic technique and control strategies are reported for each disease. The main and widespread bacterial disease, caused by Pseudomonas savastanoi pv. savastanoi, is the olive knot. As concerns the most important and widespread fungal diseases, in this text are described the olive leaf spot, Verticillum wilt, cercosporiosis, anthracnose, fruit rot, parasitic brusca, root rot, sooty mold and wood rot. Infections caused by viruses are generally symptomless and do not result in diseased plants. Although, viruses do not cause detrimental disease on olive varieties, the infected olive trees represent a reservoir of virus inoculum for other crops, where these viruses are known to cause severe disease. Detection of these viruses represent an important critical step in the sanitary improvement of this crop. Recently, molecularbased assays have been effectively implemented to detect at least 8 of the 15 viruses known to infect this crop. Sanitation program using in vitro culture of shoot tip and thermotherapy have been recently described to recover virus-free plantlets.Realizzato nell'ambito del progetto "Ricerca ed Innovazione per l'Olivicoltura Meridionale", finanziato dal MiPAAFMiPAAF - Ministero delle politiche agricole alimentari e forestal

Potato virus X in Tunesian grapevines

Two biologically distinct strains of potato potexvirus X (PVX) were recovered by sap inoculation from vines of cvs Carignan and Grenache in two different Tunisian localities. In a Grenache vineyard, PVX was detected by ELISA in about 4 % of the vines. Morphological, physico-chemical, serological and ultrastructural properties of both PVX strains from grapevine were the same as those of ordinary isolates of the type species, as shown by the results of comparative investigations. PVX seemed little pathogenic to grapevines, and was re-inoculated to grape rootlings with difficulty

Tingkat Pemanfaatan Fasilitas Dasar Dan Fungsional Untuk Peningkatan Produksi Di Pangkalan Pendaratan Ikan Tanjungsari Kabupaten Pemalang

Fishing port is an important aspect in the development of fisheries. Fishing port is the place that made up the land and surrounding waters with certain limits as the governmental activities and the activities of the fishing business systems that are used as berths and loading and unloading of fish. The purpose of this study was to analyze the level of utilization of basic and functional facilities that exist in the Tanjungsari Fishing port. The method used in collecting data of this study is descriptive method and case studies. Descriptive method is a method of data collection surveys and direct observation in the field and do pangumpulan data by focusing on an intensive and detailed case. Based on the results obtained a conclusion that is basic and functional condition of the facility at Fish Landing Base Tanjungsari Pemalang in less optimal conditions. The utilization rate of basic facilities and functional Tanjungsari Fishing port as follows: The Land Use by 87%; cruise line by 89%; the dock by 90% and 83% of the auction building. Strategy to increase the utilization of basic facilities and is a functional Tanjungsari Fishing port opitimal use of basic facilities, functional and support in order to increase fish production; Provide counseling and socialization on a regular basis to business Tanjungsari fishery in relation to the increase in fish production; Improve fishing technology such as the use of GPS and Fishfinder to increase the catch

An inverse validation for detecting pipe leaks with a TDR-based method

Recently, an innovative system based on time domain reflectometry (TDR) for the individuation of leaks in underground pipes has been proposed and validated. Starting from the results obtained so far, the present works aims at further investigating the practical applicability of the aforementioned system. In particular, the goal of this work is to assess the system in the detection of two close leaks (i.e. leakages that may occur on the same length of pipe). To this purpose, an experimental setup was arranged: two "leakage conditions" were imposed, and the position of the leaks were considered as unknown and calculated through the dedicated developed algorithm. Results show that, differently from traditional leak detection methods (in which the presence of a leak may "mask" the presence of other leaks), the TDR-based system successfully individuates and correctly localizes the presence of two leaks

Analyzing the potential biological determinants of autism spectrum disorder: From neuroinflammation to the kynurenine pathway

Autism Spectrum Disorder (ASD) etiopathogenesis is still unclear and no effective preventive and treatment measures have been identified. Research has focused on the potential role of neuroinflammation and the Kynurenine pathway; here we review the nature of these interactions. Pre-natal or neonatal infections would induce microglial activation, with secondary consequences on behavior, cognition and neurotransmitter networks. Peripherally, higher levels of pro-inflammatory cytokines and anti-brain antibodies have been identified. Increased frequency of autoimmune diseases, allergies, and recurring infections have been demonstrated both in autistic patients and in their relatives. Genetic studies have also identified some important polymorphisms in chromosome loci related to the human leukocyte antigen (HLA) system. The persistence of immune-inflammatory deregulation would lead to mitochondrial dysfunction and oxidative stress, creating a self-sustaining cytotoxic loop. Chronic inflammation activates the Kynurenine pathway with an increase in neurotoxic metabolites and excitotoxicity, causing long-term changes in the glutamatergic system, trophic support and synaptic function. Furthermore, overactivation of the Kynurenine branch induces depletion of melatonin and serotonin, worsening ASD symptoms. Thus, in genetically predisposed subjects, aberrant neurodevelopment may derive from a complex interplay between inflammatory processes, mitochondrial dysfunction, oxidative stress and Kynurenine pathway overexpression. To validate this hypothesis a new translational research approach is necessary